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Publications

Shen, Q., Zhang, Q., Shi, Y., Shi, Q., Jiang, Y., Gu, Y., Li, Z., Li, X., Zhao, K., Wang, C., Li, N.  

and Cao, X., 2018. Tet2 promotes pathogen infection-induced myelopoiesis through mRNA  

oxidation. Nature, 554(7690), pp.123-127.  

Y-Y, Z., Z-Y, F., J, W., W, Q., G, B., J, L., Y-J, M., S-Y, G., H, Y., S-Y, J., Y-F, L., H-H, M., Y, L., Y,  

W., B-L, L., Y-T, M. and B-L, S., 2018. A LIMA1 variant promotes low plasma LDL cholesterol  

and decreases intestinal cholesterol absorption. Yearbook of Paediatric Endocrinology.  

Huang, L., Jin, J., Deighan, P., Kiner, E., McReynolds, L. and Lieberman, J., 2013. Efficient  

and specific gene knockdown by small interfering RNAs produced in bacteria. Nature  

Biotechnology, 31(4), pp.350-356.  

Zhu, H., Wang, N., Yao, L., Chen, Q., Zhang, R., Qian, J., Hou, Y., Guo, W., Fan, S., Liu, S.,  

Zhao, Q., Du, F., Zuo, X., Guo, Y., Xu, Y., Li, J., Xue, T., Zhong, K., Song, X., Huang, G. and  

Xiong, W., 2018. Moderate UV Exposure Enhances Learning and Memory by Promoting a  

Novel Glutamate Biosynthetic Pathway in the Brain. Cell, 173(7), pp.1716-1727.e17.  

Xu, X., Xu, J., Wu, J., Hu, Y., Han, Y., Gu, Y., Zhao, K., Zhang, Q., Liu, X., Liu, J., Liu, B. and  

Cao, X., 2021. Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to  

Activate Macrophage Innate Response. Cell, 184(5), pp.1393-1394  

(

Gao et al., 2018)  

Gao, L., Wu, K., Liu, Z., Yao, X., Yuan, S., Tao, W., Yi, L., Yu, G., Hou, Z., Fan, D., Tian, Y., Liu,  

J., Chen, Z. and Liu, J., 2018. Chromatin Accessibility Landscape in Human Early Embryos  

and Its Association with Evolution. Cell, 173(1), pp.248-259.e15.  

Feng, Y., Wang, Y., Wang, X., He, X., Yang, C., Naseri, A., Pederson, T., Zheng, J., Zhang, S.,  

Xiao, X., Xie, W. and Ma, H., 2020. Simultaneous epigenetic perturbation and genome imaging  

reveal distinct roles of H3K9me3 in chromatin architecture and transcription. Genome Biology,  

21(1).  

Li, M., Ding, X., Zhang, Y., Li, X., Zhou, H., Yang, L., Li, Y., Yang, P., Zhang, X., Hu, J., Nice, E.,  

Wu, H. and Xu, H., 2020. Antisense oligonucleotides targeting lncRNA AC104041.1 induces  

antitumor activity through Wnt2B/β-catenin pathway in head and neck squamous cell  

carcinomas. Cell Death & Disease, 11(8).  

Pan, J., Fang, S., Tian, H., Zhou, C., Zhao, X., Tian, H., He, J., Shen, W., Meng, X., Jin, X. and  

Gong, Z., 2020. lncRNA JPX/miR-33a-5p/Twist1 axis regulates tumorigenesis and metastasis of  

lung cancer by activating Wnt/β-catenin signaling. Molecular Cancer, 19(1).  

Peng, F., Xu, J., Cui, B., Liang, Q., Zeng, S., He, B., Zou, H., Li, M., Zhao, H., Meng, Y., Chen, J.,  

Liu, B., Lv, S., Chu, P., An, F., Wang, Z., Huang, J., Zhan, Y., Liao, Y., Lu, J., Xu, L., Zhang, J.,  

Sun, Z., Li, Z., Wang, F., Lam, E. and Liu, Q., 2020. Oncogenic AURKA-enhanced  

N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in  

breast cancer stem-like cells. Cell Research, 31(3), pp.345-361.  

Chen X, Liu X, Zhang Y, et al. Methyltransferase Dotll preferentially promotes innate IL-6 and IFN-βproduction by mediating H3K79me2/3 methylation in macrophages. Cellular & Molecular Immunology. 2018 Oct 1.

Shen Q, Zhang Q, Shi Y, et al. Tet2 promotes pathogen infection-induced myelopoiesis through mRNA oxidation. Nature. 2018 Feb 1; 554(7690): 123-7.

Xu X, Xu J, Wu J, et al. Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response. Cell. 2018 Nov 29; 175: 1-16.

Zhang Y Y, Fu Z Y, Wei J, et al. A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption. Science. 2018 Jun 8; 360(6393): 1087-92.

Zhao W D, Liu D X, Wei J Y, et al. Caspr1 is a host receptor for meningitis-causing Escherichia coli. Nature Communications. 2018 Jun 12; 9: 2296.

Zhu H, Wang N, Yao L, et al. Moderate UV Exposure Enhances Learning and Memory by Promoting a Novel Glutamate Biosynthetic Pathway in the Brain. Cell. 2018 Jun 14; 173: 1-12.

Ge W, Zhao K, Wang X, et al. Iaspp Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding. Cancer Cell. 2017 Nov 13; 32: 1-13.

Lin C, Wang Y1, Wang Y2, et al. Transcriptional and posttranscriptional regulation of HOXA13 by lncRNA HOTTIP facilitates tumorigenesis and metastasis in esophageal squamous carcinoma cells. Oncogene. 2017.

Peng F, Wang J H, Fan W J. Glycolysis gatekeeper PDK1 reprograms breast cancer stem cells under hypoxia. Oncogene. 2017.

Xu L Z, Li S S, Zhou W, et al. p62/SQSTM1 enhances breast cancer stem-like properties by stabilizing MYC mRNA. Oncogene. 2017; 36: 304-17.

Zhang K, Li Y, Guo Y, et al. Elevated progranulin contributes to synaptic and learning deficit due to loss of fragile X mental retardation protein. Brain. 2017 Nov 20.

Zhou Z, Li H, Wang K, et al. Bioreducible Cross-Linked Hyaluronic Acid/Calcium Phosphate Hybrid Nanoparticles for Specific Delivery of siRNA in Melanoma Tumor Therapy. ACS Applied Materials & Interfaces. 2017; 9: 14576-89.

Huang D, Duan H, Huang H, et al. Cisplatin resistance in gastric cancer cells is associated with HER2 upregulation-induced epithelial-mesenchymal transition. Scientific reports. 2016 Feb.

Ji M, Li P, Sheng N, et al. Sialic acid-targeted nanovectors with phenylboronic acid-grafted polyethylenimine robustly enhance siRNA-based cancer therapy. ACS Applied Materials & Interfaces. 2016 Mar 23; 8(15): 9565-76.

Sang Y, Tang J, Li S, et al. LncRNA PANDAR regulates the G1/S transition of breast cancer cells by suppressing p16INK4A expression. Scientific reports. 2016 Mar. 

Xu C F, Zhang H B, Sun C Y, et al. Tumor acidity-sensitive linkage-bridged block copolymer for therapeutic siRNA delivery. Biomaterials. 2016 May; 88: 48-59. 

Xu J, Li J, Lin S, et al. Nanocarrier‐Mediated Codelivery of Small Molecular Drugs and siRNA to Enhance Chondrogenic Differentiation and Suppress Hypertrophy of Human Mesenchymal Stem Cells. Advanced Functional Materials. 2016 Apr 19; 26(15): 2463-72.

Yu C, Ji S Y, Dang Y J, et al. Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse. Cell research. 2016; 26(3): 275-87.

Yue X, Cao D, Lan F M, et al. MiR-301a is activated by the Wnt/β-catenin pathway and promotes glioma cell invasion by suppressing SEPT7. Neuro-Oncology. 2016 Mar 22.

Zhang C G, Zhu W J, Liu Y, et al. Novel polymer micelle mediated co-delivery of doxorubicin and P-glycoprotein siRNA for reversal of multidrug resistance and synergistic tumor therapy. Scientific Reports. 2016 Mar 31. 

Zhang Y Y, Wang Y Q, Wei Y H, et al. Molecular chaperone CCT3 supports proper mitotic progression and cell proliferation in hepatocellular carcinoma cells. Cancer letters. 2016 Mar 1; 372(1): 101-9.

Zhao Y, Ma T, Chen W, et al. MicroRNA-124 promotes the intestinal inflammation by targeting AHR in Crohn’s disease. Journal of Crohn's and Colitis. 2016 Jan 22. 

Huang G W, Liao L D, Li E M, et al. siRNA induces gelsolin gene transcription activation in human esophageal cancer cell. Scientific Reports. 2015 Jan 20; 5: 7901-5.

Jiang L, Huang J, Li L, et al. MicroRNA-93 promotes ovarian granulosa cells proliferation through targeting CDKN1A in polycystic ovarian syndrome. The Journal of Clinical Endocrinology & Metabolism. 2015 Feb 19.

Liu Y, Song Z M, Deng X, et al. Chitosan-coated red fluorescent protein nanoparticle as a potential dual-functional siRNA carrier. Nanomedicine. 2015 Jul; 10(13): 2005-16.

Ma L, Li Y, Peng J, et al. Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration. Cell research. 2015; 25(1): 24-38.

Ni F, Zhao H, Cui H, et al. MicroRNA-362-5p promotes tumor growth and metastasis by targeting CYLD in hepatocellular carcinoma. Cancer Letters. 2015 Jan 28; 356(2): 809-18. 

Yang J, Liu W, Lu X, et al. High expression of small GTPase Rab3D promotes cancer progression and metastasis. Oncotarget. 2015 May 10; 6(13): 11125-38.

Zheng Q, Hou J, Zhou Y, et al. Siglec1 suppresses antiviral innate immune response by inducing TBK1 degradation via the ubiquitin ligase TRIM27. Cell Research. 2015 Oct; 25: 1121-36. 

Zhuang WZ, Ge XP, Yang SJ, Huang ML, Zhuang WY, Chen P, Zhang XH, Fu JX, Qu J, Li BZ. Upregulation of lncRNA MEG3 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells From Multiple Myeloma Patients By Targeting BMP4 Transcription. Stem Cells. 2015 Jun; 33(6): 1985-97.

 
siRNA Oligos
MicroRNA Oligos
DNA Cloning and Mutagenesis
Lentivirus, Adenovirus (ADV), and Adeno-associated virus (AAV) vectors
miRNA Hairpin-it qPCR Kit & Other Kits
siRNA mate and GP-transfect-Mate
RNA FISH Probe and Kit
The Experiment of Animals
The Experiment of Fluorescein Report
Aptamer